Our lab is interested in presynaptic physiology focusing on the mechanisms that regulate neuronal development and aging
Previous and current research
Our overall goal is to elucidate the molecular principles underlying protein turnover in the brain, with a particular focus on neuronal development and aging.
We are also working on a series of labeling techniques using super-resolution microscopy and mass spectrometry technologies to study protein stability and turnover in vitro and in vivo in various model systems.
Projects and collaborations
Current projects in the lab aim to:
In the future, we will extend the use of metabolic labeling to other model organisms and biological conditions, and explore the possibility of using impulse labeling to address a more general set of dynamic questions in brain biology.
Our close collaborators include Prof. Dr. Silvio O. Rizzoli (University Medical School, Göttingen) and Dr. Felipe Opazo (Center of Biostructural Imaging of Neurodegeneration, Göttingen).